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With the discovery of the molecular structure of the DNA double helix in 1953, researchers turned to the structure of ribonucleic acid (RNA) as the next critical puzzle to be solved on the road to understanding the molecular basis of life. Indeed, RNA may be the only molecule to have inspired the formation of a club, known as the RNA Tie Club, whose members included Nobel Laureates James Watson and Francis Crick, the discoverers of DNA structure, as well as Sydney Brenner, who was awarded the Nobel Prize in 2002 for his work involving gene regulation in the model organism Caenorhabditis elegans. The members of this club, each nicknamed for a particular amino acid, exchanged letters in which they presented various unpublished ideas in an attempt to understand the structure of RNA and how this molecule participates in the building of proteins. During the following 50 years, many questions were answered, and many surprises were uncovered along the way.

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Date Of Record Release 2009-09-03 16:34:03
Description With the discovery of the molecular structure of the DNA double helix in 1953, researchers turned to the structure of ribonucleic acid (RNA) as the next critical puzzle to be solved on the road to understanding the molecular basis of life. Indeed, RNA may be the only molecule to have inspired the formation of a club, known as the RNA Tie Club, whose members included Nobel Laureates James Watson and Francis Crick, the discoverers of DNA structure, as well as Sydney Brenner, who was awarded the Nobel Prize in 2002 for his work involving gene regulation in the model organism Caenorhabditis elegans. The members of this club, each nicknamed for a particular amino acid, exchanged letters in which they presented various unpublished ideas in an attempt to understand the structure of RNA and how this molecule participates in the building of proteins. During the following 50 years, many questions were answered, and many surprises were uncovered along the way.
Classification
Resource Type
Format
Subject
Source Nature Education
Keyword RNA, Genetics, DNA
Date Of Record Creation 2009-09-03 16:28:42
Education Level
Date Last Modified 2009-10-12 15:48:34
Creator Suzanne Clancy
Language English
Date Record Checked: 2009-09-03 00:00:00 (W3C-DTF)

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